{"id":430,"date":"2026-09-14T13:07:21","date_gmt":"2026-09-14T11:07:21","guid":{"rendered":"https:\/\/asmed.net\/?page_id=430"},"modified":"2026-09-15T13:02:09","modified_gmt":"2026-09-15T11:02:09","slug":"disturbi-umore-e-comportamento","status":"publish","type":"page","link":"https:\/\/asmed.net\/en\/tecnologia\/indicazioni-terapeutiche\/disturbi-umore-e-comportamento\/","title":{"rendered":"Disturbi dell’umore e del comportamento"},"content":{"rendered":"

\nTherapeutic Indications \u00b7 Mood and Behavior Disorders\n<\/p>

\nDisorders of mood and behavior: when the treatment pathway needs one more option.\n<\/h1>

\nFor the doctor and psychologist who follow patients with anxiety, depression or stress-related disorders and evaluate a complementary, non-invasive and drug-free option. On this page: what exists, what has been studied, with what limits.\n<\/p><\/div><\/section>

\nIn practice\n<\/p>

\nWhen the response is partial\n<\/h2>

\nIn outpatient practice, some patients with anxiety, depression or stress-related disorders respond partially to the set pathway \u2013 pharmacological, psychotherapeutic or combined. This is no exception: It is a stable share of daily work.\n<\/p>

\nWhen that happens, the options that remain almost always come at a cost: a change or addition of medication, with timing and tolerability to manage; a frequency of sessions that not everyone supports; Or the wait. The room for manoeuvre narrows precisely where it would be most useful.\n<\/p>

\nIt is in this space that it makes sense to consider a complementary option \u2014 provided that it is non-invasive, applicable with standardised protocols and can be integrated into the route without replacing it.\n<\/p><\/div>

\"Three-dimensional<\/div><\/div><\/section>

\nWhat exists\n<\/p>

\nREAC\u00ae protocols for this area\n<\/h2>

\nFor mood and behavior disorders REAC\u00ae Technology provides neuromodulation protocols of the Neuro Psycho Physical Optimization family, applied with the medical device BENE Mod 110. The scope, as defined in the technical documentation, includes depressive and anxiety disorders, emotional dysregulation and stress-related disorders.\n<\/p><\/div>

\n01\n<\/span>

\nNPO \u2013 Neuro Postural Optimization\n<\/h3>

\nA single ear application of 500 milliseconds. In the technical documentation it is also indicated for the initial neurophysiological regulation of vegetative and emotional functions; Study DASS-42 of 2019 precedes the NPPO cycle.\n<\/p><\/div>

\n02\n<\/span>

\nNPPO \u2013 Neuro Psycho Physical Optimization\n<\/h3>

\nPoint application on the auricle with the handpiece probe: seven pulses of 500 milliseconds per session, in cycles of 18 sessions. Reserved for doctors and psychologists trained on technology.\n<\/p><\/div>

\n03\n<\/span>

\nNPPO-CB \u2014 Cervico Brachial\n<\/h3>

\nSurface application on the cervicobrachial area with the ACP electrode, held in place by a tubular network: about four minutes per session, in cycles of 18 sessions. For doctors, dentists and psychologists.\n<\/p><\/div><\/div>

\nThe treatment is painless, occurs on intact skin and, according to the technical documentation, there are no known contraindications to the concomitant use of pharmacological therapies.\n<\/p>

\nDevice and Protocols \u2192\n<\/a><\/div><\/div><\/section>

\nWhat literature says\n<\/p>

\nWhat has been studied\n<\/h2>

\nTwelve clinical publications by Rinaldi and Fontani (2009\u20132025) on anxiety, depression and stress-related disorders are indexed on PubMed. These include: a randomised double-blind versus placebo study, a single-blind versus placebo analysis in 888 subjects, a controlled study with an untreated group and some case series. Here the main ones, with design and number.\n<\/p><\/div>

\nPsychometric evaluation of a radio electric auricular treatment for stress related disorders: a double-blinded, placebo-controlled pilot study\n<\/h3>

\nHealth and Quality of Life Outcomes \u00b7 2010\n<\/p>

\nRandomized, double-blind, placebo-controlled (pilot study) \u00b7 200 participants (150 treated, 50 placebo) \u00b7 adults with stress-related symptoms \u00b7 PSM scale, 18 sessions in 4 weeks \u00b7 registered with ANZCTR.\n<\/p>\nView on PubMed \u2192\n<\/a><\/article>

\nStress-related psycho-physiological disorders: randomized single blind placebo controlled naturalistic study of psychometric evaluation using a radio electric asymmetric treatment\n<\/h3>

\nHealth and Quality of Life Outcomes \u00b7 2011\n<\/p>

\nRandomized, single-blind, placebo-controlled, naturalistic \u00b7 888 participants \u00b7 NPPO protocol, 4-week cycle \u00b7 PSM scale \u00b7 ANZCTR registered. The same cohort is analysed in two other publications (Indian Journal of Medical Research 2010; Patient Preference and Adherence 2012).\n<\/p>\nView on PubMed \u2192\n<\/a><\/article>

\nRadio electric asymmetric conveyer neuromodulation in depression, anxiety, and stress\n<\/h3>

\nNeuropsychiatric Disease and Treatment \u00b7 2019\n<\/p>

\nControlled with untreated group, not blinded \u00b7 DASS-42 scale prior to treatment and approximately three months later \u00b7 NPO and NPPO protocols \u00b7 number not reported in the abstract.\n<\/p>\nView on PubMed \u2192\n<\/a>\nRead the summary in the News \u2192\n<\/a><\/article>

\nRadioelectric brain stimulation in the treatment of generalized anxiety disorder with comorbid major depression in a psychiatric hospital: a pilot study\n<\/h3>

\nNeuropsychiatric Disease and Treatment \u00b7 2011\n<\/p>

\nPilot study, open, without control group \u00b7 24 patients \u00b7 generalized anxiety disorder with major depression in comorbidity, in drug treatment \u00b7 HAM-D and SCL-90-R scales.\n<\/p>\nView on PubMed \u2192\n<\/a><\/article><\/div>

\nThe limits to know: controlled studies use self-administered scales; three publications analyse the same cohort; the most recent work is a series of cases; 2010\u20132012 studies were conducted with the previous generation of the device, with the same technology.\n<\/p>

\nAll publications on PubMed\n<\/a><\/div><\/div><\/section>

\nFrequently Asked Questions\n<\/p>

\nBefore evaluating it: the most frequently asked questions\n<\/h2><\/div>
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